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Overexpression of Plakophilin2 mitigates capillary leak syndrome in severe acute pancreatitis by activating the p38/MAPK signaling pathway

Graphical Abstract Similar content being viewed by others Introduction The articular cartilage is an avascular connective tissue with limited self-repair capacity [1, 2]

support to energy metabolism 23,24,25 , counteraction of glutamate excitotoxicity 28,29 , oxidative stress 30,31,32 and cellular death 33,34 , expression of plasticity-related and pro-survival genes 33,34 , and protection of astrocytes 35 )