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Cobalamin deficiency, hyperhomocysteinemia, and dementia

Data points represent adjusted % change from baseline mean, where adjustment is for subscore baseline value and treatment

This gives it the name cobalamin. Unlike most other vitamins, B12 acts as a coenzyme in two critical biochemical reactions: Conversion of homocysteine to methionine Enzyme : Methionine synthase Why it matters : This reaction supports methylationa process that affects DNA synthesis, neurotransmitter production, and detoxification pathways

10.1158/1078-0432.Ccr-16-1789 Clin