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Probiotic bacteria are amazing little chemical manufacturing plants

Research using cell culture models such as Calu-3 airway epithelial cells, has demonstrated that these cytokines affect the integrity and permeability of pulmonary epithelial barrier integrity by regulating key TJs proteins like occludin, claudin-2, and ZO-1

Moreover, in some conditions there may be an ectopic production of thyroid hormones, leading to increased thyroid hormones and a compensatory decrease of TSH, Table 1 (Oo KM n.d