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Among nucleotide tri-phosphates like ATP, GTP hydrolysis selectively drives energy-dependent cellular processes of protein synthesis and vesicular trafficking, including endocytosis and autophagy [7]

However, early treatment may be suitable if severe gynecomastia impacts a patient's quality of life

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Banuls C, Rovira-Llopis S, Martinez de Maranon A, Veses S, Jover A, Gomez M, Rocha M, Hernandez-Mijares A, Victor VM (2017) Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte-endothelium interactions in PCOS

These findings are supported by (i) the decreased GPx1 mRNA in intestinal macrophages, and (ii) the decreased GPx1 protein observed in biopsies from inflamed gut regions from individuals with CD, although the immunohistochemistry did not co-stain for macrophage markers