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however, human studies remain limited and inconclusive, highlighting the necessity for further investigation

For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%)

doi: 10.1093/brain/aws262

Statements Author contributions LW: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing original draft, Writing review & editing