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A GWAS of middle-aged and older adults aged 4069 years reported that the heritability of age-related hearing loss (ARHL) was estimated to be between 35 and 55% (Wells et al., 2019)

Waldman AD, Fritz JM, Lenardo MJ

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Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux

confirmed that selenium nanoparticles alleviate pain associated with OA by suppressing the production of ROS in IL-1-stimulated cells and enhancing GPX activity, which in turn inhibits the NF-B p65 and p38/MAPK signaling pathways [124]