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doi:10.1177/1535370213477988 Maddocks ODK, Labuschagne CF, Adams PD, Vousden KH (2016) Serine metabolism supports the methionine cycle and DNA/RNA methylation through de novo ATP synthesis in cancer cells

At the same time, it was found that DHT could induce the expression of HSD17B2 mRNA and protein in endometrial cancer cells [177]

Cognitive impairment found in type 2 diabetes can progress to Alzheimer's disease by inducing vascular dysfunction and oxidative stress

PLoS Pathog 9 , e1003660 (2013)

However, some of the studies used injected SAMe, which may not have the same effects as SAMe taken as a dietary supplement