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The untreated and MSO-treated parasite pellets isolated by saponin treatment were pooled separately during solubilization with 6 M urea in 25 mM ammonium bicarbonate buffer

This decline is particularly pronounced in metabolically active tissues such as brain, muscle, and liver, where NAD+ levels can decrease by 70% or more during aging

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Cell death, particularly chondrocyte death, represents a critical event in OA pathology, involving multiple pathways including apoptosis and ferroptosis (Xiang et al., 2023)

I stumbled upon this Wikipedia page and learned about the importance of things like Brain-derived neurotrophic factor (BDNF)