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Lastly we identified a POAG-associated intronic variant on chromosome 9 which encodes UBAP2 , a gene associated with the neurodegenerative disease amyotrophic lateral sclerosis 44 ,in which astrocytes play a role in both ALS disease and in changes to the optic nerve head in glaucoma 45

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The increase in serum sodium could be a result of the transition from intravenous to oral diuretic therapy or might be a result of the observed RAAS suppression as has been noted in people 28

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