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however, disease progression is characterized by early M1-dominant pro-inflammatory responses followed by pathological M2 predominance (Mestan et al., 2025

A possible link between astrocyte activation and tau nitration in Alzheimers disease

Nevertheless, ferroptosis may also trigger immunosuppression and immunotherapy resistance in gliomas due to their unique tumor microenvironment, where ferroptosis inhibition might be beneficial [140]