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3 BDNF Hippocampus mRNA Increase in BDNF exon III mRNA in the hippocampus after a single dose (Dolotov et al., 2006) 7 AA Heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro sequence ACTH(4-10) + stabilizing tripeptide Pro-Gly-Pro 813.93 Da Molecular Weight Formula CHNOS CAS 80714-61-0 | Purity 98% HPLC DA/5-HT Neurotransmitters Activation of the brain's dopaminergic and serotonergic systems (Eremin et al., 2005) Russia 2011 Approved List of Vital and Essential Medicines of the Russian Federation (Stroke, cognition) Mechanism of Action Neurotrophin & Neuroprotection Upregulation of BDNF/trkB, dopaminergic/serotonergic activation and anti-ischemic neuroprotection Primary Route BDNF/trkB Upregulation of Neurotrophic Factor Semax rapidly increases BDNF levels (1.4x protein, 3x exon III mRNA) and phosphorylation of its receptor trkB (1.6x) in the hippocampus after a single administration of 50 g/kg

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Moreover, Bae et al

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The Cafs will benefit participants in many ways, including learning about the area in which they live, meeting new people and improving confidence in using English in speaking, writing, reading and listening The Summer Reading Challenge concluded with 1,018 children signing up to join the challenge, with the theme Story Garden

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