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In conjunction with its cofactor NADPH, TXNRD (also termed TrxR) catalyzes the disulfide reduction of TXN [50]

I recommend selenomethionine due to its high bioavailability (21)

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Deficiency of Fe-S compromises mitochondrial quality, including its disorganized cristae, less cristae, and less mitochondrial number, resulting in mitochondrial dysfunction (reviewed in [3])