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doi: 10.3389/fphar.2022.829966 144

Following this observation, they also show that recovering physiological levels of this modification by treatment with the histone deacetylase inhibitor SAHA restores the expression of learning-induced genes and the cognitive abilities of old mice

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This multi-layered regulatory mechanism weakens the differentiation of naive T cells into anti-tumor Th1 cells while promoting their differentiation into pro-tumor Th2 cells