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In a mouse model of sepsis-induced AKI, the expression of the deubiquitinating enzyme USP10 was decreased

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however, the epigenetic regulatory mechanisms involved remain under investigation

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Three patients (11.5%) were able to stop DEX between 17-24 hours, while 6 patients (23.1%) could only discontinue DEX after 24 hours or more following clonidine administration

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Quinolinic acid also modulates macrophage functioning, and drives immune tolerance through N-methyl-D-aspartate (NMDA) receptor and peroxisome proliferator-activated receptor gamma (PPAR) signaling (110)

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ChemBioChem 10 (6), 9991006

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