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33 In addition, endothelial cells treated with GSH exhibit blockade of NF-B activity decreased expression of NF-B downstream target gene inter-cellular adhesion molecule-1 (ICAM-1)

ATP adenosine triphosphate the relatively unusual peptide bond via the gamma-carboxyl group of glutamic acid prevents uncontrolled degradation of the glutathione molecule by peptidases

Once in the tissues, ALA can be found inside and outside the cells including inside the mitochondria where it functions naturally as a coenzyme for the oxidation of pyruvate, alpha ketoglutarate, and branched-chain amino acids.*