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The peptide facilitates the formation of new synapses and enhances the plasticity of existing neuronal connections, which are essential processes for learning and memory

This structural relationship has made Dihexa useful for comparative investigations of angiotensin-derived compounds, structure-activity relationships, peptide-derived signaling modulators, and the molecular determinants governing receptor-associated signaling pathways.

The shared C-terminal Pro-Gly-Pro motif of both peptides is associated with increased resistance to enzymatic degradation

Novo Nordisk's combined expertise in GLP-1 and amylin chemistry enabled this approach