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6 Supplementation of GSH in cystine-free conditions rescues downstream products of cysteine metabolism

& van Leyen, K

On the other hand, mitochondrial autophagy, as a means for cells to deal with stress, may contribute to cell survival

This means that the clinical effectiveness of GSHand that of its precursors like NACis dependent not only on its capability to act as an antioxidant, but also the degree to which their pharmacodynamic properties are in line with the dysfunction in cellular signaling, redox imbalance, and immune response generated by specific disease states (Chai and Mieyal, 2023