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Heterozygotes: Have approximately 50% enzyme activity but without cyanosis

Methods Enzymol 299:152178 Skalicka-Wozniaka K, Erdogan Orhan I, Cordell GA, Nabavi SM, Budzynska B (2016) Implication of coumarins towards central nervous system disorders

Surface refinement Enzymatic exfoliation supports smoother-looking skin

doi: 10.3390/pharmaceutics12070684

The MITF gene encodes a basic-helix-loop-helix leucine zipper (bHLH-ZIP) transcription factor that homo- or heterodimerizes with the related transcription factors: TFEB, TFE3 and TFEC