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Mar 2015;14(2):140-148

Numerous research studies have shown improved outcomes of combination treatments

The length of ICU stays and the need for endotracheal intubation in the LC group were significantly less than in the control group ( P 0.05, Table 1)

For example, Papokastas and colleagues 5 found that treatment of major depressive disorder (MDD) with 15mg of Lmethylfolate in conjunction with an SSRI showed significantly greater efficacy compared to SSRI therapy alone regarding response rate and degree of change in depression symptom scores