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CDPI shows several advantages over the nebulized solution form, including shorter administration (1 min) and an enhanced portability (Conole and Keating, Fluoroquinolones Fluoroquinolones belong to the family of quinolones, a group of molecules that is widely used as antibiotic because of their large spectrum of bactericidal activity, excellent bioavailability, rapid cellular uptake (Drusano, 1997

Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P)

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This allows for rapid absorption and a more pronounced effect on cellular antioxidant capacity

Besides damaging the functions of these molecules, oxidative stress also triggers a series of cellular responses, including the activation of PKC, NF-B, and JNK stress-associated kinases [13]