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Blinatumomab in standard-risk B-cell acute lymphoblastic leukemia in children

The new formulation was indicated as antioxidant mix (MIX)

IGF-1 contains three disulphide bridges, between amino acids 6 and 48, 18 and 61 and 47 and 52, which create the tertiary structure critical for optimum binding to the IGF-1R (Figure 1)