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Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy

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One of the main criteria for classifying variants is to categorize them into null variants, which result in a non-functional protein or no protein at all, and missense variants, which produce a protein with an altered amino acid sequence that may retain residual function, have reduced function, or even acquire a different function from the original protein

Ions generated in the ionization unit are accelerated in the Z-direction by a relatively-weak voltage of only a few dozen volts

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