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In homozygotes, microglial and astrocyte activation appeared at 12 months, neuronal loss in the hippocampus and entorhinal cortex at 24 months, and synaptic loss at 8 months

It is commonly referenced in metabolic regulation research, including enzymatic and cellular pathway investigations

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153 Through culturing BALF cells of COPD patients with healthy individuals, it was found that MMP-9 release by macrophages in COPD patients was significantly increased while healthy control macrophages released more TIMPs