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It therefore appears that the reduction of A levels is insufficient to treat AD, and therefore calls into question the centrality of the amyloid hypothesis. Thus, we discuss the important biological functions of the A peptide, which could illuminate the less-than-satisfactory results of these anti-amyloid therapies

Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements

H., Leventhal, B

Moreover, intra-articular administration of sprifermin has been applied for patients with acute cartilage injury of the knee (NCT01066871), where treatment outcomes revealed reductions in both defect volume and cartilage defect thickness