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Double-strand DNA sensing Aim2 inflammasome regulates atherosclerotic plaque vulnerability

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While the most common underlying comorbidities are reported to be obesity, hypertension, diabetes, underlying cardiovascular and lung disease, people with immune-mediated diseases such as autoimmune disease, and those on immune-suppresants or immune-modulating drugs may also be more vulnerable to this infection

Naqash AR, Ricciuti B, and Owen DH, et al (2020) Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort Cancer Immunol Immunother 69 (7) 11771187 PMID: 32140762 51