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www.geteyesmart.org/eyesmart/eye-health-news/press-releases/20110401.cfm, accessed 11-18-11

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However, exposure to alcohol triggers the activation of HSCs, leading to the loss of retinol storage and their trans-differentiation into myofibroblasts, which secrete ECM.10 This activation is driven by factors such as TGF-1, ROS, lipid peroxides, PDGF and epidermal growth factor.79 80 Recent studies have expanded the understanding of HSC functions beyond ECM production

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