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10.1001/jamapediatrics.2015.2125 201 MezianeH.SchallerF.BauerS.VillardC.MatarazzoV.RietF.et al

In terms of monitoring, it is advisable to conduct monthly tests for B12, Hcy and MMA during the initial 6 months, followed by tests every 36 months in LCIG patients (Jia et al

Statements Author contributions ZH: Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

While human trials are still underway, early results are promising, with some patients reporting reduced pain and improved mobility after intra-articular GHK-Cu injections

Consistent with these biological roles, cytokine analysis revealed that EGCG-Zn significantly downregulated the pro-inflammatory cytokines IL-6 and TNF- while upregulating the anti-inflammatory cytokine IL-10 (Fig