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Specifically, in secretion-competent INS-1E cells and isolated mouse islets (186), butyrate significantly attenuates IL-1- or IL-1/IFN--induced apoptosis by suppressing endoplasmic reticulum (ER) stress, while reducing the production of nitric oxide (NO) and chemokines (CXCL1, CXCL10) that amplify immune cell infiltration

It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

& Vestergaard, M

10.1007/s13346-017-0439-7 Drug Delivery Transl Res

A 100mg vial only delivers its cost advantage if you actually use the material within that window a large vial reconstituted and then mostly discarded is less economical than buying 50mg as needed