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Despite this instability, animal models consistently show that cryptotanshinone produces a more pronounced dose-dependent suppression of the NF-B p65 complex and superior systemic anti-inflammatory outcomes compared to tanshinone IIA (Maione et al., 2018)

A few commenters noted that CMS requires collection of Health-Related Social Need (HRSN) data across multiple setting-specific programs and stated that repeated screenings could result in duplicative efforts and be counter-productive to building trust with patients