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ROC analysis of adduct levels in serum from patients known to have APAP hepatotoxicity showed that an APAP protein adduct level 1.1 nmol/mL had a high sensitivity and specificity (96.8 and 95.0 %, respectively) for patients with APAP overdose and ALT levels above 1000 IU/L

Saudi J Biol Sci 27:28832889

Most cases show RMSD values below 1 and high per-residue confidence (high predicted local distance difference test [pLDDT] values) across the whole structure

Analytical testing methods provide definitive degradation assessment but require specialized equipment

The cells treated with Rosup (50 mg/ml) for 30 min were used as positive controls