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[DOI] [PubMed] [Google Scholar] 75.Barrett KE, Keely SJ

Chen Q, et al

An imbalance in mitochondrial dynamics has been observed in conditions of iron overload [126]

ROS can also inhibit the mTOR-P70S6K signaling cascade leading to decreased protein synthesis for proliferation and differentiation [172]

Defective mitochondria enhance neuronal susceptibility to apoptosis and interact with other cellular stress sources, such as inflammation and DAMP signaling [69]