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It functions as a transporter of fatty acids into the mitochondria, the powerhouse of the cell

Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible

In vitro studies have demonstrated that SSZ is a non-competitive inhibitor of the reduced folate carrier which allows folate and MTX transport across the cell membrane, and therefore, hypothetically, could reduce MTX effectiveness or cause a lack of synergistic effects [16]