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Ludewig B, Graf D, Gelderblom HR, Becker Y, Kroczek RA, Pauli G

Clinical pharmacokinetics and metabolism of irinotecan (CPT-11)

The one piece of cleaner support is Sun 2021 (PMID 34827486), an independent group's APP/PS1 mouse study reporting improved Morris water maze performance, increased synaptophysin, and reduced IL-1/TNF- via PI3K/AKT