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The incidence of cutaneous melanoma has increased rapidly worldwide.15 Although it corresponds to only 4% of all skin cancers, it accounts for 80% of skin cancer deaths.4 Because early detection of the disease is implicit in its cure and only 14% of patients with metastatic disease survive beyond 5 years,46 knowledge of factors that increase an individual's risk for developing melanoma and diagnosis at an early stage of the disease have great prognostic relevance

Researchers must calculate injection volume based on target dose using this formula: injection volume (mL) = target dose (mg) peptide concentration (mg/mL)

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The diagnosis is established clinically

Research protocols administer MT-1 injection 3060 minutes before controlled UV exposure for this reason