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Mechanistically, SSP intermediates couple to the TCA cycle, where PSAT1 catalyzes the conversion of 3-PHP to PS while simultaneously converting GLU to -KG, thereby channeling GLU-derived carbon into the TCA flux (58)

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Another example might be the mutagenesis of a single codon position (i.e

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Identification and characterization of a novel snat2 (slc38a2) inhibitor reveals synergy with glucose transport inhibition in cancer cells