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Marraccini, T

Treatment impact on patient-reported outcomes in peripheral neuropathic pain: comparing single intervention with topical high-concentration capsaicin to daily oral pregabalin

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Supporting this interpretation, a previous clinical study reported that individuals carrying SNPs associated with reduced GLUT2 expression exhibit greater responsiveness to metformin, further suggesting that decreased intestinal glucose absorption mediated by reduced expression of glucose transporters such as GLUT2 may play an important role in enhancing overall glucose homeostasis after metformin administration 52

Then the GLU, GLY, glutamine and taurine were analyzed using an LC-Q-TOF-MS system (SCIEX 5600, MA, United States) in negative ionization mode, and chromatographic separation was performed on a Waters Bridge Amide column (3.5 m, 4.6 100 mm)