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Melatonin suppresses iron-induced neurodegeneration in rat brain

Roux-en-Y gastric bypass surgery (RYGB) but not sleeve gastric bypass surgery or gastric banding, increases the risk of vitamin B 12 deficiency and requires preventive post-operative treatment with either injected or high-dose oral supplementation

The impact results in a rapid and irreversible loss of neuronal protection, as well as a decrease in the number of synapses and dendritic spines

GSH NAC Forman HJ, Zhang H, Rinna A

Comparing Clinical Evidence: GLP-1 Receptor Agonists vs Antioxidant Therapy Randomized controlled trials of semaglutide, including SUSTAIN and STEP studies, consistently show significant weight loss, improved blood sugar control, and reduced cardiovascular risk markers