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Since the formation of stable metal-thiolate complexes precludes the direct thiol-disulfide redox potential measurements by usual electrochemical techniques, an indirect method had to be elaborated

However, the formation of selenoxide could be observed when the cyclization is blocked by replacing the N-H moiety in compound with an N-Et group

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Glutathione S-transferases catalyzed conjugation of 1,4-disubstituted butanes with glutathione in vitro