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Atherosclerosis is primarily characterized by inflammation, disrupted blood flow, and arterial wall remodeling, substantially influenced by excess reactive oxygen species (ROS) (He and Zuo 2015)

Serratia bacteria and Acinetobacter calcoaceticus that found in the human gut can cleave the 3-hydroxybutyryloxy group of L-carnitine to directly produce TMA (Meadows and Wargo, 2015)

Infants And children The recommended oral dosage for infants and children is between 50 and 100 mg/kg/day in divided doses, with a maximum of 3 g/day

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