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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Broedbaek K, Ribel-Madsen R, Henriksen T, Weimann A, Petersen M, Andersen JT, Afzal S, Hjelvang B, Roberts LJ, 2nd, Vaag A, Poulsen P, Poulsen HE

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The high fat content results in elevated levels of dopamine across the reward circuits of the brain (138)

Early intervention helps prevent complications and ensures proper treatment for any underlying issues

One study showed NR at 300 mg/day increased human blood NAD+ ~50% after 8 weeks, whereas higher doses (1000 mg/day) roughly doubled NAD+ levels