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doi: 10.1007/s00277-018-3539-7 89 GimferrerENomdedeuJGichIJess BarcelMBaigetM

Results indicate that the prevalence of intestinal barrier dysfunction is higher in patients with hypertension than in those without hypertension [45, 85,86,87,88]

In 1970, Orlowski and Meister proposed the -glutamyl cycle, which includes the synthesis, breakdown, export and import of GSH as a key process for amino acid uptake (Orlowski and Meister, 1970)

The pathogenesis of MTX-induced renal impairment is thought to be mediated by either MTX and its metabolites precipitating in the renal tubules or MTXs direct toxic impact on the renal tubules (Reference Widemann and Adamson6)

10.3390/polysaccharides2030033 30 DickerK