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Moreover, the metabolites of arginine play an important role in maintaining the intestinal barrier and promoting the repair of the gastrointestinal mucosa ( + cells and activate CD4 + T lymphocytes, leading to inflammatory/immune-mediated diseases ( + /CD8 + in different parts of intestinal mucosal immunity decreased significantly after 8 weeks of TGP administration in this study, suggesting that TGP may regulate lymphocytes in intestinal mucosal immunity and epithelial barrier through glutathione metabolism, thereby exerting an anti-RA effect

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Drug Development Research , 80 , 360367

In CF sputum, fexlamose induced a larger decrease in elastic modulus (G'), achieved a 50% reduction in G more rapidly, and caused mucolysis of a larger proportion of sputum samples within 15 minutes compared to NAC and dornase alfa