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Once in the systemic circulation, these enzymes act as systemic anti-inflammatories

Mavrommatis E, Shioura KM, Los T, Goldspink PH (2013) The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction

Extracellular glutamate is efficiently taken up by the sodiumdependent excitatory amino acid transporters (EAAT) 1 and 2 (Todd and Hardingham 2020), while glycine uptake is mediated by the sodiumdependent transporters GlyT1 and GlyT2 (Marques et al