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2018) demonstrated a significant increase in the GSH/GSSG ratio in the brain of patients with PD after NAC administration, indicating enhanced redox balance and reduced oxidative stress

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Extensive research indicates that NRF2 plays a pivotal role in regulating ferroptosis due to its diverse functions in iron, lipid, and amino acid metabolism (Shakya et al., 2023

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F.GuidottiG.BrambillaL.RossiD

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