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discovered a suppressive impact of soluble UA on the TLR signaling pathway in monocytes [51](Fig

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This was especially interesting given that expression of Hgf and Met , encoding the HGF receptor tyrosine kinase, is expressed in the early developing SV, and HGFMET signaling has been shown to be crucial to the incorporation of melanocytes into the SV (Shibata et al., 2016)

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