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Liver tissue samples were collected from the donor and from patient 2 h after reperfusion

As mentioned in the Section 1, the Prx Tpx1 is the main scavenger of H 2 O 2 during aerobic growth [23], and cytosolic Trx1 and Trx3 recycle disulfide-linked Tpx1 dimers at the expense of reduced cofactor [33] (Fig

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Bonkovsky and co-workers have demonstrated that CoPP, and ZnMP upregulate HO-1 expression through the repression of Bach1 and upregulation of the Nrf2 protein (Shan et al., 2006

Moreover, the unclear regulatory relationship between the H3K14la/PMCA2 axis and microglial pyroptosis further undermines the theoretical foundation for targeting the integrated neurovascularimmune cell death network