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This can also be addressed with orthotics by properly aligning the feet and cushioning the impact to decrease overall pressure up the leg during activity

Functional milestones Functional improvements often tell you more than pain scores alone: Walking distance without symptom increase Sitting tolerance (minutes before symptoms worsen) Ability to perform previously limited activities Sleep quality (reduced nighttime symptoms indicate improvement) Medication usage (decreasing NSAID use is a positive sign) When to adjust the protocol If there is no improvement after 3 to 4 weeks on a BPC-157 only protocol, consider adding TB-500 for systemic support

2008, 3: CD004159

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Most patients begin noticing subtle changes within the first few weeks, such as feeling fuller faster, fewer cravings, and more stable energy throughout the day