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As with vitamin B9 deficiency, vitamin B12 deficiency is also associated with megaloblastic anaemia due to the vitamins vital role in DNA synthesis (Socha et al, 2020)

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In addition, mucus contains secretory immunoglobulin A, antimicrobial products, peptides trefoil (trefoil factor family, TFF), cathelicidins, and ribonucleases, which are responsible for reinforcing the physical separation of the microbiota, forming a gradient from the epithelium to the lumen [11]