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Design of BNBMs with suitable biomechanics Substantial studies over the past 20 years have established that the mechanical properties of the ECM affect cellular proliferation, growth, migration, differentiation and other behaviors

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doi: 10.20892/j.issn.2095-3941.2019.0353 102 RaychaudhuriBRaymanPIrelandJKoJRiniBBordenECet al

Our roGFP2 measurements confirm (i) that dynamic roGFP2 sensing (or the physiological glutathionylation/deglutathionylation of regular surface-exposed cysteinyl residues) requires a glutaredoxin activity, and (ii) that glutathionylated proteins or metabolites should be very transient redox species when GSH and glutaredoxins are present (unless they are stabilized by a kinetic uncoupling mechanism) 5,32,34,35,61,62,63,64