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"One patient presented with multisystem involvement with the mucocutaneous lesions being the only clue for the early diagnosis of vitamin B12 deficiency." The study concluded that unexplained and ongoing skin issues might indicate a vitamin B12 deficiency

[DOI] [PubMed] [Google Scholar] 366.Yin K., Agrawal D.K

In the mucosal cells of the distal ileum, the B12-IF complex is recognized by special receptors

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The resin is functionalized with an acid labile linker that allows for acidic cleavage usually trifluoroacetic acid, hydrofluoric acid (HF) or trifluoromethanesulfonic acid